Self Assessment Questions for Lesson 19 Identification and Structure of Genomic Information by Dr Jamie Love 2002 - 2005

What is the difference between a nucleotide and a nucleoside?

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#2

Draw a pyrimidine. Any pyrimidine will do - indeed, just draw a general structure, without the side groups which distinguish one pyrimidine from another.

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#3

Now draw a general purine.

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#4

Draw a ribose and a deoxyribose.

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#5

Draw (as best you can) cytidylate (or any nucleotide) showing all the atoms.

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#6

List the purines, give their one letter abbreviation and match them with the correct (hydrogen bond paired) pyrimidine also with their abbreviation - and tell me the number of hydrogen bonds the pairs form.

Tell me which pair (purine to pyrimidine) is found exclusively in DNA and which pair is found exclusively in RNA.

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#7

Write the complementary sequence (the one that forms hydrogen bonds) to this sequence…

GATACAA

(Remember that we are using the shortest of shorthand representation here, so be sure you have the direction correct.)

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#8

Now that you have learned two ways to find the complementary sequence. Let's do another.

Write the complement to CTATGTT.

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#9

OK, I think you are getting the hang of writing complementary sequences but I have one more for you to try.

Write the complement of GAATTC.

(Hint - go with what you know, check your answer and, regardless of how strange the answer, trust your judgment.)

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#10

The haploid human genome is estimate to have three billion bases pairs. Using the information about the distances between bases that you learned in this lesson, estimate the total length of a single haploid human genome.

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This work was created by Dr Jamie Love and licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.